Leigh Marcus Selected Research

satraplatin (JM 216)

4/2015	Phase 1 trial and pharmacokinetic study of the oral platinum analog satraplatin in children and young adults with refractory solid tumors including brain tumors.
1/2012	The plasma and cerebrospinal fluid pharmacokinetics of the platinum analog satraplatin after intravenous administration in non-human primates.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Leigh Marcus Research Topics

Disease

6	Neoplasms (Cancer) 01/2021 - 01/2012
3	Fatigue 01/2021 - 04/2015
3	Colorectal Neoplasms (Colorectal Cancer) 01/2021 - 06/2017
3	Thyroid Neoplasms (Thyroid Cancer) 01/2015 - 02/2012
2	Nausea 01/2021 - 06/2017
2	Microsatellite Instability 01/2021 - 01/2019
2	Diarrhea 01/2021 - 06/2017
2	Asthenia 01/2021 - 06/2017
2	Brain Neoplasms (Brain Tumor) 04/2015 - 01/2012
2	Multiple Endocrine Neoplasia Type 2b (MEN 3) 01/2015 - 08/2013
1	Heart Failure 01/2021
1	Vision Disorders (Hemeralopia) 01/2021
1	Hyperuricemia 01/2021
1	Hematologic Neoplasms (Hematological Malignancy) 09/2020
1	Lymphoma (Lymphomas) 09/2020
1	Leukemia 09/2020
1	Febrile Neutropenia 06/2017
1	Anemia 06/2017
1	Thrombocytopenia (Thrombopenia) 06/2017
1	Fever (Fevers) 06/2017
1	Vomiting 06/2017
1	Abdominal Pain (Pain, Abdominal) 06/2017
1	Neutropenia 06/2017
1	Headache (Headaches) 04/2015
1	Hypothyroidism 01/2015
1	medullary Thyroid cancer 01/2015
1	Neoplasm Metastasis (Metastasis) 02/2012

Drug/Important Bio-Agent (IBA)

3	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2019
3	pembrolizumabIBA 01/2021 - 01/2019
2	Pharmaceutical PreparationsIBA 01/2021 - 09/2020
2	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2019 - 06/2017
2	Irinotecan (Camptosar)FDA LinkGeneric 01/2019 - 06/2017
2	PlatinumIBA 04/2015 - 01/2012
2	satraplatin (JM 216)IBA 04/2015 - 01/2012
2	vandetanib (ZD6474)IBA 01/2015 - 08/2013
1	tyrosine receptor (receptor, tyrosine)IBA 01/2021
1	entrectinibIBA 01/2021
1	Phosphotransferases (Kinase)IBA 01/2021
1	PanobinostatIBA 09/2020
1	A 7 (A-7)IBA 01/2019
1	trifluridine tipiracil drug combinationIBA 06/2017
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 06/2017
1	ElectrolytesIBA 04/2015
1	EnzymesIBA 04/2015
1	Thyroxine (Levothyroxine)FDA LinkGeneric 01/2015
1	Thyroid HormonesIBA 01/2015
1	indium-111-octreotideIBA 02/2012
1	Somatostatin Receptors (Somatostatin Receptor)IBA 02/2012
1	Cisplatin (Platino)FDA LinkGeneric 01/2012

Therapy/Procedure

3	Therapeutics 01/2021 - 01/2015
2	Drug Therapy (Chemotherapy) 06/2017 - 01/2015
1	Drug Tapering 06/2017
1	Biological Therapy 06/2017
1	Thyroidectomy 01/2015